Typical Treatment for Skin Rejuvenation

Anti-age treatment has come a long way from traditional techniques like Botox and hyaluronic acid injections. Today, advanced procedures like AFI+ (Autologous Fibroblast Injection) and Exosome Therapy offer remarkable, long-lasting results using the body’s own regenerative power. These innovative techniques are recognized as the best performing and personalised practices for revitalising ageing derm, assuring a youthful look without relying on artificial substances.

What is AFI+?

AFI+ is a breakthrough in derm revitalising, emphasising the use of personalised, autologous fibroblast injections. This method surpasses conventional mesotherapy and PRP (Platelet-Rich Plasma) by utilising the patient’s own cells—specifically, fibroblasts. These cells, dutiful for the skin’s structure, tensility, and hydration, decrease with age, resulting in ageing lines and diminished skin firmness. AFI+ rejuvenates the derm by replenishing lost fibroblasts, stimulating the cellular recovering process, and restoring ageless firmness and elasticity. The effect is a lively and revitalised countenance that lasts for years, eliminating the need for frequent follow-up procedures.

The Principles of Fibroblasts in AFI+

Fibroblasts are the cornerstone of derm health, producing key elements like collagen and elastin that maintain skin’s structure and resilience. Collagen provides strength and elasticity, while elastin allows the skin to return to its original shape after stretching. Over time, the number of fibroblasts diminishes, resulting in fine lines, wrinkles, and decreased firmness. AFI+ addresses this natural decline by harvesting fibroblasts from the patient’s own skin, growing them in a specialised environment—the AFI culture laboratory—and reintroducing millions of these cells into the skin through targeted injections. This autologous approach not only avoids the risks of immune rejection but also ensures a completely natural rejuvenation process.

The Three-Step Procedure of AFI+

The AFI+ treatment is a straightforward yet highly specialised three-step procedure:

1. Biopsy: The process begins with a small skin sample, usually from a discreet area like the back of the earlobe. The biopsy, only 3mm in size, is painless due to local anaesthesia.
2. Fibroblast Cultivation: In the AFI culture laboratory, fibroblasts from the sample are isolated and cultivated in optimal conditions. Over a period of 4-6 weeks, the cell count grows from a few hundred to 40-50 million. These cells are preserved under cryogenic conditions for potential future use.
3. Injection: The cultivated fibroblasts are then injected back into the patient’s skin, targeting areas that need rejuvenation. Advanced micro-needle technology, such as the Micronjet® device, ensures precise delivery into the dermis. Results start to show within 3-4 months, with peak improvements continuing for up to 6 months post-treatment.

This process leads to gradual yet lasting improvements, with effects lasting for several years, making AFI+ a superior choice over short-term filler solutions.

Enhancing Skin Rejuvenation with Exosome Therapy

Exosome Therapy represents another frontier in regenerative medicine. Exosomes, or extracellular vesicles, are tiny carriers of bioactive molecules like proteins, peptides, and growth factors, which facilitate intercellular communication. They are derived from mesenchymal stem cells (MSCs) and play a crucial role in regenerating and revitalising the skin. When applied to skin rejuvenation, exosomes boost collagen synthesis, enhance elasticity, and improve overall skin health.

How Exosome Therapy Works

Exosomes are harvested from MSCs, formulated into a potent solution, and delivered directly to target areas through injections or IV drips. These vesicles stimulate the skin’s natural healing process by binding to existing cells, initiating repair and regeneration. Exosome therapy not only addresses fine lines, wrinkles, and sagging skin but also promotes a brighter, smoother, and plumper complexion by stimulating collagen production up to six times and increasing elastin levels by over 30%. This makes exosome therapy a powerful ally in combating the effects of ageing and environmental damage, such as UV exposure and pollution.

Advantages of AFI+ and Exosome Therapy Over Traditional Methods

1. Long-Term Results: Unlike Botox or hyaluronic acid, which require regular maintenance, both AFI+ and Exosome Therapy provide results that last for years due to the body’s natural cell production.
2. Personalised Approach: Both treatments use the patient’s own cells or cell derivatives, eliminating the risk of allergic reactions and ensuring a natural rejuvenation process.
3. Natural Regeneration: These methods stimulate the body’s innate healing mechanisms, promoting collagen, elastin, and hyaluronic acid production. This leads to firmer, more elastic, and youthful skin without altering facial expressions, which is a common downside of fillers.

Treating Wrinkles, Scars, and More

Wrinkles are a natural consequence of ageing, exacerbated by the loss of collagen and elastin in the dermal matrix. Areas around the eyes, forehead, lips, and between the eyebrows are particularly prone to these changes. Acne scars and other skin imperfections can also result from a decrease in fibroblast activity. AFI+ and Exosome Therapy provide solutions that go beyond masking these imperfections—they work at a cellular level to regenerate the skin from within, creating long-lasting, natural results.

Safety and Clinical Proven Results

Both AFI+ and Exosome Therapy have undergone extensive clinical research. AFI+, first introduced in 1995, has been validated through clinical trials involving over 2000 patients, demonstrating its efficacy and safety. This method, recognized by the FDA, has become a gold standard in natural skin rejuvenation. Similarly, Exosome Therapy, though a newer innovation, has shown promising outcomes in regenerative medicine with minimal risks. The key to a successful treatment lies in seeking care from certified specialists who adhere to proper extraction and preparation protocols to minimise any risks.

Comparing Fibroblast and Exosome Therapies

Conclusion

AFI+ and Exosome Therapy are at the forefront of a new era in skin care, offering advanced, personalised solutions for ageing and damaged skin. By utilising the body’s own regenerative capabilities—whether through autologous fibroblasts or stem cell-derived exosomes—these treatments deliver superior, long-lasting results without the frequent need for artificial substances. If you’re seeking to rejuvenate your skin naturally and effectively, these innovative therapies provide the most advanced options available, transforming the way we approach anti-aging treatments today.