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Home News Science High-Intensity Focused Ultrasound (HIFU) for Cancer

High-Intensity Focused Ultrasound (HIFU) for Cancer

Published:
May 5, 2025

For decades, cancer treatment meant one of three things: surgery, chemotherapy, or radiation. Most people still hear the word cancer and picture those options. But medicine has been slowly shifting toward more focused, less invasive approaches – and High-Intensity Focused Ultrasound, or HIFU, is part of that shift.

It’s not new, exactly. Doctors began experimenting with ultrasound for cancer as early as the mid-20th century. But it’s only in recent years that the technology has started gaining ground – especially in areas like prostate cancer treatment, where precision really matters.

A Different Kind of Treatment

HIFU doesn’t involve cutting, and it doesn’t use radiation. Instead, it uses concentrated sound waves to heat and destroy small areas of tissue – typically tumor cells – while sparing the healthy tissue around them. The process takes place inside the body, guided by imaging tools like MRI or real-time ultrasound.

In most cases, patients go home the same day. There’s no hospital stay, and recovery tends to be quicker compared to surgery or radiation. That makes it especially appealing for people looking into alternative cancer treatment options, or those unable to tolerate more aggressive therapies.

Why Prostate Cancer?

So far, HIFU has seen the most use in treating localized prostate cancer. It’s not the first line of defense for everyone, but for some men, it offers a middle ground – less invasive than surgery, and with fewer long-term side effects than radiation.

Not everyone qualifies. If the cancer has spread outside the prostate, HIFU usually isn’t recommended. It’s best suited for early-stage cases, often when the tumor is small and contained.

Still, for many patients, it offers a balance: targeted treatment with a lower risk of urinary or sexual dysfunction – two common concerns with more traditional prostate cancer treatment methods.

Photo of Shenzhen Genoimmune Medical Institute (GIMI)

Shenzhen Genoimmune Medical Institute (GIMI)

China
Shenzhen, China
The Shenzhen Geno-Immune Medical Institute (GIMI) stands at the forefront of gene and immune cell therapy, pioneering innovative solutions beyond FDA-approved CAR-T treatments. Led by renowned expert Prof. Lung-Ji Chang, inventor of the widely-adopted lentiviral vector system, GIMI has delivered effective treatments for over 1,000 cancer cases with cutting-edge 4th generation CAR-T technologies.

A Broader Movement in Cancer Care

HIFU is just one of several new techniques cancer researchers are exploring. Others include immunotherapies, gene-targeted drugs, and even electrical fields that interfere with cancer cell division. The goal in all of these? Do less harm to the body while still controlling – or in some cases eliminating – the disease.

The science behind HIFU is still evolving. Long-term data is limited, and the results can vary depending on tumor type, location, and individual biology. But what’s clear is that interest is growing – not just from patients, but from oncologists who see HIFU as another tool in an expanding toolbox.

What About Safety?

It’s a fair question. Newer treatments can feel untested. But HIFU has been studied in clinical settings for years, and early results suggest it’s generally safe when used appropriately. Most complications, when they occur, are mild and temporary.

And no – HIFU does not involve radiation. That’s one of its defining features. For some people, avoiding radiation is a priority, either due to past exposure or concerns about long-term effects. HIFU gives those patients another option.

That said, there are still limitations. HIFU isn’t available everywhere. It may not be covered by all insurance plans. And some tumors are simply not located in places where focused ultrasound can reach them safely.

So who isn’t a good candidate? Typically, people with more advanced cancer, where the disease has already spread, are advised to consider other options. Also, HIFU doesn’t usually work well on tumors near bones or gas-filled organs, which can block or distort the ultrasound waves.

The Trade-Offs, Explained Simply

Like most cancer treatments, HIFU isn’t perfect. It’s not always a one-and-done procedure. Some people may need additional sessions, or even follow-up treatments later on. And while the risk of side effects is lower than with surgery or radiation, it’s not zero.

The most commonly reported downsides include:

  • temporary urinary issues;
  • mild discomfort or swelling in the treated area;
  • in rare cases, erectile dysfunction (especially in prostate applications).

But for many patients, especially those looking for a less invasive or alternative cancer treatment, those risks may be acceptable trade-offs.Just send us a request through our website, and we’ll match you with a specialist who’s the right fit for your needs. We work with experienced professionals across a wide range of oncology institutions to help you get the care you deserve.

Does HIFU have radiation?

No. One of HIFU’s advantages is that it doesn’t use radiation at all. Instead, it relies on ultrasound energy to heat and destroy cancerous tissue.

What is the disadvantage of HIFU?

While it’s less invasive, HIFU doesn’t work for all cancer types or stages. In some cases, cancer may return or require further treatment. Availability and insurance coverage can also be a barrier.

Is high intensity focused ultrasound safe?

Generally, yes. HIFU is considered safe when performed by trained professionals in appropriate clinical settings. Side effects tend to be fewer and milder compared to surgery or radiation.

Who is not a candidate for HIFU?

Patients with metastatic cancer or tumors in difficult-to-reach areas may not be suitable for HIFU. The treatment is most effective for localized tumors that can be clearly targeted with imaging.

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